10. Stolyarov MV, Lyubovtseva LA, Moskovskiy AV, Kandeykina NV. Immunohistochemical exploration of jaw bone tissue defect after toothprotecting operations

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UDC 611.716:616.31

DOI: 10.15507/0236-2910.026.201604.533-547

IMMUNOHISTOCHEMICAL EXPLORATION OF JAW BONE TISSUE DEFECT AFTER TOOTHPROTECTING OPERATIONS

Maksim V. Stolyarov
assistent of Oral and Maxillofacial Surgery and Dentistry Chair, Ulyanov Chuvash State University (15, Moskovskiy Ave., Cheboksary, Russia), ORCID: http://orcid.org/0000-0001-6637-189X, This email address is being protected from spambots. You need JavaScript enabled to view it.

Lyubov A. Lyubovtseva
head of General and Clinical Morphology and Forensic Medicine Chair, Ulyanov Chuvash State University (15, Moskovskiy Ave., Cheboksary, Russia), Dr.Sci. (Biology), professor, ORCID: http://orcid.org/0000-0002-2818-568X , This email address is being protected from spambots. You need JavaScript enabled to view it.

Aleksandr V. Moskovskiy
professor of Prosthetic Dentistry and Orthodontics Chair, Ulyanov Chuvash State University (15, Moskovskiy Ave., Cheboksary, Russia), Dr.Sci. (Medicine), ORCID: http://orcid.org/0000-0003-1356-027X, This email address is being protected from spambots. You need JavaScript enabled to view it.

Nataliya V. Kandeykina
associate professor of Prosthetic Dentistry and Orthodontics Chair, Ulyanov Chuvash State University (15, Moskovskiy Ave., Cheboksary, Russia), Ph.D. (Medicine), ORCID: http://orcid.org/0000-0003-0430-336X, This email address is being protected from spambots. You need JavaScript enabled to view it.

Introduction: The article deals with the process of new bone formation within one year after toothprotecting operations. Various bone-seeking materials of autogenic, allogenic and xenogeneic origin are used in the process. The authors studied the cellular composition of the jaw postoperative defect for selecting the optimal osteoplastic filler in toothprotecting operations.
Materials and Methods: 32 toothprotecting operations were carried out during the study period. The healthy jaw bone tissue was obtained during intake of teeth according to orthodontic indicators. The research was conducted using immunohistochemical methods in 3, 7, 30, 90, 120, 150, 180 and 360 days after operation.
Results: Reduction of the number of CD68-positive cells is marker of proliferation of Ki-67 in the postoperation period.
Discussion and Conclusions: The cell populations in the bone tissue defect are found in the state of active proliferation. The intensity of proliferative activity in groups of research decreases in the period after operation.

Keywords: toothprotecting operation, bone tissue defect, osteotropic material, immunohistochemistry, Alloplant, Osteomatrix

For citation: Stolyarov MV, Lyubovtseva LA, Moskovskiy AV, Kandeykina NV. Immunohistochemical exploration of jaw bone tissue defect after toothprotecting operations. Vestnik Mordovskogo universiteta = Mordovia University Bulletin. 2016; 4(26):533-547. DOI: 10.15507/0236-2910.026.201604.533-547

Acknowledgements: The authors express their gratitude to head of mortuaries of Chuvash Republic Clinical Oncologic Dispensary Ye. Moskvichev for help in the study.

This work is licensed under a Creative Commons Attribution 4.0 License.